Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry.
نویسندگان
چکیده
The combination of stable isotope labelling with direct infusion ion mobility mass spectrometry (IM-MS) enabled qualitative and quantitative monitoring of biocatalytic reactions with reduced analysis times, enhanced sensitivity and μL-level assay volumes. The new approach was demonstrated by applying to both lipase and monooxygenase enzymes, including multi-substrate screening.
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ورودعنوان ژورنال:
- The Analyst
دوره 141 8 شماره
صفحات -
تاریخ انتشار 2016